The City of Maysville has a City Manager form of government in which the city commission employs a city manager to handle the day-to-day operations of the city as provided by Kentucky Regulatory Statute 83A.150.

The City of Maysville has a five member Board of Commissioners, including the Mayor, which sets policy through municipal orders, resolutions, and ordinances.

The Board of Commissioners meets on the second and fourth Thursdays of each month at 5:15 p.m. at Maysville Municipal Building, 216 Bridge Street, Maysville, KY 41056. Meetings are also live-streamed via Zoom and the City’s YouTube page.